Preparation and synthesi

Colostrinin was originally identified by scientists working in Poland in the 1970s. Colostrinin is derived from colostrum, which is present in the pre-milk fluid produced from mammary glands in the first few days after parturition. It is also known as proline-rich polypeptides, since sequence analysis of the peptides present in this mixture reveals an unusually high proportion of this amino acid residue. The amino acid compositions of Colostrinin from ovine, bovine, and human colostrum are very similar. Colostrinin was first characterized in animal and in-vitro studies as a substance that generally stimulates the immune response. Such an immunomodulatory action may be important in the treatment of a variety of diseases and is consistent with the beneficial effect of colostrum in promoting the development of the immune system in newborn mammals.